A wonderful gift for Grandma!
wood slices (flat slab of wood, a bit bigger than a handprint. You can get these at Wal-Mart or a craft store)
picture of child
Cover child's hand in fabric paint, and put a handprint on the wood. Cut the picture out into a fun shape, and cut a piece of construction paper a bit bigger in the same size to make a border around it. Glue paper and picture on board. Let glue and paint dry, then cover with 2-3 coats of matte finish modge podge.
We did ours on a larger piece of wood and did all three of our kids' handprints and a group picture. Also, add the dates, the kid's names, and a saying like "Happy Mother's Day" if you want!